Bioperl 1.5.1


I am pleased to announce the 1.5.1 developer release of Bioperl.

Essential links here Core http://bioperl.org/DIST/bioperl-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-1.5.1.zip http://bioperl.org/DIST/bioperl-1.5.1.tar.bz2

Run http://bioperl.org/DIST/bioperl-run-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-run-1.5.1.zip http://bioperl.org/DIST/bioperl-run-1.5.1.tar.bz2

Ext http://bioperl.org/DIST/bioperl-ext-1.5.1.tar.gz http://bioperl.org/DIST/bioperl-ext-1.5.1.zip http://bioperl.org/DIST/bioperl-ext-1.5.1.tar.bz2

MD5 sum http://bioperl.org/DIST/SIGNATURES.md5

Please see my mailing list post for more information.

I have appended the Change log from Bioperl core compents below 1.5.1 Developer release

o Major problem with how Annotations were written out with Bio::Seq is fixed by reverting to old behavior for Bio::Annotation objects.

o Bio::SeqIO

- genbank.pm \* bug #1871; REFLOOP’ parsing loop, I changed the pattern to expect at l east 9 spaces at the beginning of a line to indicate line wrapping.

\* Treat multi-line SOURCE sections correctly, this defect broke both common_name() and classification()

\* parse swissprot fields in genpept file

\* parse WGS genbank records

- embl.pm \* Changed regexp for ID line. The capturing parentheses are the same, the difference is an optional repeated-not-semi- colon expression following the captured S+. This means the regexp works when the division looks like /PRO;/ or when the division looks like /ANG ;/ - the latter is from EMBL repbase

\* fix ID line parsing: the molecule string can have spaces in it. Like: “genomic DNA”

- swiss.pm: bugs #1727, #1734

- entrezgene.pm \* Added parser for entrezgene ASN1 (text format) files. Uses Bio::ASN1::EntrezGene as a low level parser (get it from CPAN)

o Bio::AlignIO

- maf.pm coordinate problem fixed

o Bio::Taxonomy and Bio::DB::Taxonomy

- Parse NCBI XML now so that nearly all the taxonomy up-and-down can be done via Web without downloading all the sequence. o Bio::Tools::Run::RemoteBlast supports more options and complies to changes to the NCBI interface. It is reccomended that you retrieve the data in XML instead of plain-text BLAST report to insure proper parsing and retrieval of all information as NCBI fully expects to change things in the future. o Bio::Tree and Bio::TreeIO

- Fixes so that re-rooting a tree works properly

- Writing out nhx format from a newick/nexus file will properly output bootstrap information. The use must move the internal node labels over to bootstraps. for my $node ( grep { ! $_->is_Leaf } $tree->get_nodes ) { $node->bootstrap($node->id); $node->id(’’); } - Nexus parsing is much more flexible now, does not care about LF.

- Cladogram drawing module in Bio::Tree::Draw

- Node height and depth now properly calculated

- fix tree pruning algorithm so that node with 1 child gets merged

o Graphics tweaks. Glyph::xyplot improved. Many other small-medium sized bugs and improvements were added, see Gbrowse mailing list for most of these.

o Bio::DB::GFF partially supports GFF3. See information about gff3_munge flag in scripts/Bio-DB-GFF/bulk_load_gff.pl.

o Better location parsing in Bio::Factory::FTLocationFactory - this is part of the engine for parsing EMBL/GenBank feature table locations. Nested join/order-by/complement are allowed now

o Bio::PrimarySeqI->translate now takes named parameters

o Bio::Tools::Phylo::PAML - parsing RST (ancestral sequence reconstruction) is now supported. Parsing different models and branch specific parametes are now supported.

o Bio::Factory::FTLocationFactory - parse hierarchical locations (joins of joins)

o Bio::Matrix::DistanceMatrix returns arrayrefs instead of arrays for getter/setter functions

o Bio::SearchIO

- blast bug #1739; match scientific notation in score and possible e+ values

- blast.pm reads more WU-BLAST parameters and parameters, match a full database pathname,

- Handle NCBI WEB and newer BLAST formats specifically (Query|Sbjct:) match in alignment blocks can now be (Query|Sbjct).

- psl off-by-one error fixed

- exonerate parsing much improved, CIGAR and VULGAR can be parsed and HSPs can be constructed from them.

- HSPs query/hit now have a seqdesc field filled out (this was always available via $hit->description and $result->query_description

- hmmer.pm can parse -A0 hmmpfam files

- Writer::GbrowseGFF more customizeable.

o Bio::Tools::Hmmpfam make e-value default score displayed in gff, rather than raw score allow parse of multiple records